When the lovely naturopathic doctor tells you to take your herbal supplements with food first thing in the morning, she means it. If you try to outsmart her and take them on an empty stomach, you will pay the price. You will not only get acid reflux but it will move with a speed and force that freaks you out in rush hour traffic. You will be turning around and rushing home to get out of your brand new Jones NY suit and disinfect your car. You will then wear another suit to work and never, ever, ever take herbal supplements in a way that goes away from the directions. Trust me on this one!